What is Epigenetics?
Epigenetics and Diseases?
What is MIAMI (Genome-wide methylation analysis method using microarray) ?
Hpa II recognition site distribution and number
Strategy for MIAMI
Example of MIAMI analysis
Protocol for MIAMI

Izuho Hatada
Biological Genome Resource Center, Institute for Molecular and Cellular Regulation,Gunma University
Example of MIAMI analysis

MIAMI was applied to compare a lung cancer cell line (1-87) and a normal lung.  Among the promoters of 6,995 genes, we found that 400 (5.7%) genes were hypermethylated in cancer.

Hatada Laboratory
Biosignal Genome Resource Center
Gunma University
Institute forMolecular and
Cellular Regulation.Gunma University
Faculty of Medicine,
Gunma University
Faculty of Education,
Gunma University
Faculty of Social&Information Studies,
Gunma University
Faculty of Engineering,
Gunma University
The Ministry Education, Culture,Sports,Science and Technology specific area research
Genome Science
The Japanese Society for Epigenetics